mercoledì 22 gennaio 2020, ore 10:30 - 18:30
10:30 Introducono:
Marco DE CURTIS
Eleonora PALMA11:00 - 11:45 Intervengono:
Ganna BALAGURA,
SINEUPs: a novel targeted therapeutic approach based on ncRNAs torecover gene haploinsufficiency causing Developmental and Epileptic EncephalopathiesSara MANCINELLI,
Dissecting the role of HCN1 in Developmental and Epileptic Encephalopathy (DEE) by exploiting patient-specific models of cerebral cortex development in vivo and in vitroLidia CAROTENUTO,
A fluorescence-based assay to evaluate the activity of Kv7.2/Kv7.3 channel modulators11:45 - 12:00 Discussione:
Pasquale STRIANO
Federico ZARA
12:00 - 12:30 Intervengono:
Carmen DE CARO,
Investigation on the role of gut microbiota in the WAG/Rij rat modelAlessandro ESPOSITO,
Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome12:30 - 13:30 Light lunch
13:30 - 14:15 Intervengono:
Rosa Chiara GOISIS,
GABA tonic inhibition is deeply affected early during development in a mouse model of Dravet syndromeGabriele RUFFOLO,
GABAergic dysfunction of Hippocampal Sclerosis Linked to SCN1A Mutation with Reduced interneuronal excitabilityRossella DI SAPIA,
Cholesterol 24-hydroxylase is a new target for disease-modification in acquired epilepsy14:15 - 14:30 Discussione:
Antonio GAMBARDELLAMichele SIMONATO
15:30 - 16:00 Pausa caffè
16:00 - 16:45 Intervengono:
Caterina MICHETTI,
Excitation/inhibition imbalance and paroxysmal behavior in PRRT2 koMiriam SCIACCALUGA,
Hippocampal epileptogenesisin LGI1, CASPR2 & GABABR encephalitis: a preliminary studySimona BALDASSARRI,
Modeling autosomal dominant lateral temporal lobe epilepsy using induced pluripotent stem cells16:45 - 17:00 Discussione:
Cinzia COSTAEmilio RUSSO
17:00 - 17:30 Incontro con “YES” (Young Epilepsy Section dell’ILAE)
17:30 - 18:30 Conclusioni - Commissione di Elettrologia Sperimentale e Presidente LICE
