Convegno
Riunione policentrica in Epilettologia
mercoledì 22 gennaio 2020, ore 10:30 - 18:30
Aula Odeion
Facoltà di Lettere
Università Sapienza di Roma
piazzale Aldo Moro, 5
00185 Roma
10:30 Introducono:
Marco DE CURTIS
Eleonora PALMA

11:00 - 11:45 Intervengono:
Ganna BALAGURA, SINEUPs: a novel targeted therapeutic approach based on ncRNAs torecover gene haploinsufficiency causing Developmental and Epileptic Encephalopathies
Sara MANCINELLI, Dissecting the role of HCN1 in Developmental and Epileptic Encephalopathy (DEE) by exploiting patient-specific models of cerebral cortex development in vivo and in vitro
Lidia CAROTENUTO, A fluorescence-based assay to evaluate the activity of Kv7.2/Kv7.3 channel modulators

11:45 - 12:00 Discussione:
Pasquale STRIANO
Federico ZARA

12:00 - 12:30 Intervengono:
Carmen DE CARO, Investigation on the role of gut microbiota in the WAG/Rij rat model
Alessandro ESPOSITO, Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome

12:30 - 13:30 Light lunch

13:30 - 14:15 Intervengono:
Rosa Chiara GOISIS, GABA tonic inhibition is deeply affected early during development in a mouse model of Dravet syndrome
Gabriele RUFFOLO, GABAergic dysfunction of Hippocampal Sclerosis Linked to SCN1A Mutation with Reduced interneuronal excitability
Rossella DI SAPIA, Cholesterol 24-hydroxylase is a new target for disease-modification in acquired epilepsy

14:15 - 14:30 Discussione:
Antonio GAMBARDELLA
Michele SIMONATO

15:30 - 16:00 Pausa caffè

16:00 - 16:45 Intervengono:
Caterina MICHETTI, Excitation/inhibition imbalance and paroxysmal behavior in PRRT2 ko
Miriam SCIACCALUGA, Hippocampal epileptogenesisin LGI1, CASPR2 & GABABR encephalitis: a preliminary study
Simona BALDASSARRI, Modeling autosomal dominant lateral temporal lobe epilepsy using induced pluripotent stem cells

16:45 - 17:00 Discussione:
Cinzia COSTA
Emilio RUSSO

17:00 - 17:30 Incontro con “YES” (Young Epilepsy Section dell’ILAE)

17:30 - 18:30 Conclusioni - Commissione di Elettrologia Sperimentale e Presidente LICE